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doi: 10.1016/j.cmet.2016.02.005

People without diabetes lost an average of 20% of their body weight on average over about 16 months, which is a significant amount for a medication

Heavy, greasy, or deep-fried foods These can worsen nausea, reflux, and stomach discomfort when gastric emptying is slower

GLP-1s are thought to cause higher muscle loss (2539%) than non-pharmacological methods of weight loss, such as diet and exercise (10-30%) 29

Address Hormonal Changes: If hormonal imbalances are affecting your sex drive, consult your doctor about potential supplements or treatments to restore balance

It stands to reason that if a potentially epileptogenic ICI is employed in a seizure-vulnerable patient population, e.g., GBM, this may indirectly encourage tumor progression secondary to increased epileptiform activity and paradoxically result in decreased therapeutic efficacy