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The accumulation of senescent cells, often referred to as the "old cell burden," is a concern because these cells can secrete a variety of harmful substances as part of the senescence-associated secretory phenotype (SASP)

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Research indicates that FOXO4-DRI can selectively remove senescent cells in chondrocytes, which are the cells found in cartilage

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Additionally, it promotes angiogenesis, enhances antioxidant enzyme activity, and modulates inflammatory responses for comprehensive skin renewal

You might have to take a B12 supplement or try a new medication