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In the middle, a horizontal pathway shows homocysteine being remethylated to methionine in a reaction that requires folate in the form of 5-methylTHF and vitamin B 12

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Fundamentally, AuNCs are intriguing functional nanomaterials with a precise molecule-like structure (comprising a discrete number of gold atoms and protecting ligands) and considered as the missing link between molecules and nanoparticles 16

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DNA nanoparticles targeted to Langerhans cells have been shown to have good immune cell recruitment and induction of cellular immunity

That is a very different statement from they do nothing. It means: The mechanistic rationale is real