Rapid weight loss often means skipping exercise due to low energy, resulting in muscle and water loss
Nausea (30-40%), reduced appetite, bloating, constipation, headaches
3 References Le Roux CW, Garvey WT, Kolnes KJ, et al
Research shows that L-citrulline raises plasma L-arginine levels approximately 30% more effectively than L-arginine alone, making it the preferred choice for sustained cardiovascular support and exercise performance
So doing the trial in older people for longer is what allowed you to see that the seed oils seemed to be able to cause cancer
One mechanistic thread does point straight at this specific drug, and it deserves stating precisely, because it is the honest version of the exciting claim