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Some patients using Mounjaro for weight loss may notice heartburn or acid reflux during treatment

Individual medical needs If you have certain health conditionslike diabetes, heart disease, or kidney issuesyour doctor will factor those into the decision

10.1038/ajg.2013.451 5 AtreyaR.MudterJ.FinottoS.MllbergJ.JostockT.WirtzS.et al (2000)

Such mechanisms occur very rapidly, within 515 min upon receptor binding, indicating that the actions are not mediated by altered gene expression, but likely by phosphorylation of protein components of the secretory machinery 13

Most patients notice initial changes within 2 to 4 weeks, with more significant results at the 8 to 12 week mark

Bibcode:1994JTEHA..41..387H