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Ozempic is a glucagon-like peptide-1 (GLP-1) receptor agonist that is used: with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus
The increase in Ca 2+ is mediated by IP3 induced release of intracellular Ca 2+ and by depolarization leading to activation of voltage dependent Ca 2+ channels
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Statistical significance was determined by one-way ANOVA followed by Bonferroni post-hoc analysis
GSSG concentration is then measured by spectrophotometry with the GSH recycling method, on the basis of conversion of GSSG to GSH by glutathione reductase and NADPH and reaction with 5,5-dithiobis-(2-nitrobenzoic acid)
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