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Niosomes are fabricated through the self-aggregation of nonionic surfactants in an aqueous environment usually through the either thin film hydration or solvent injection techniques (Rigano and Lionetti, 2016

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Its broader receptor activity underlies systemic side effects: pronounced nausea, vomiting, flushing, increased blood pressure, spontaneous and sometimes painful erections (priapism), and altered mood or libido

A total of 41 patients with cirrhosis who visited the Department of Gastroenterology in Bellland General Hospital (Osaka, Japan), were asked to participate between April and September 2013 (Fig

& Kempler, P