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In addition, 2-DG uptake was markedly suppressed in tumors derived from U87 cells with the knockout of endogenous DHHC9 or GLUT1, and these suppression effects were abrogated by reconstituted expression of WT rDHHC9 or rGLUT1, but not rDHHC9 C169S or rGLUT1 C207S (Supplementary Fig
Similarly, loss of GPX-1 or GPX-5 led to increased BODIPY staining, and treatment with ML162 or Fer-1 enhanced or diminished BODIPY intensity in gpx-5 mutants respectively (Fig
Two data points were omitted from analysis in vehicle group due to extensive food spillage
Getty Images I see it every day in my office, said Dr
In this article, we'll explore what off-label medications are, how (and why) they're used and what it could mean for your care
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