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The first patient, treated in 1906, was a 50 year old dying man who had just had his toe amputated due to gangrene from diabetes and was in a diabetic coma

The 2.4 mg strength is generally used as a maintenance dose after gradual dose escalation and should not be used as the initial treatment dose

Gadani SP, Smirnov I, Smith AT, Overall CC, Kipnis J

It is possible to take this medication with or without food

GLP-1 Medication: How to Safely Decrease Your Dose | Expert Guide Why You Should Taper Gradually Stopping GLP-1 medications suddenly can throw your body off balance

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