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Proteins of the PDI family: Unpredicted non-ER locations and functions

Two reviewers independently assessed and selected studies for inclusion and subsequently resolved discrepancies by discussion

Currently, weight loss drugs like Wegovy (semaglutide) and Zepbound (tirzepatide) are very popular

If the drugs can treat or prevent psychiatric problems, the impact could be huge, given that 20% of Americans live with a mental illness and many dont have an effective treatment

The most commonly advertised contraindication is a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2

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