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Berberine is a plant alkaloid that activates AMPK, affecting glucose and lipid metabolism

A person with a BMI of 28 and a history of gestational diabetes may benefit from one of these medications to lose weight while concomitantly mastering lifestyle behaviors, and then transition off the weight management medications to lifestyle alone, says Linda Gigliotti, MS, RDN, CDCES, CSOWM, an obesity and weight management specialist based in Irvine, California

Symptomatic cases typically emerge in the fifth to sixth decades of life

Consistency in timing is more important than the specific time chosen

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