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(PubMed) Neumann WL, Coss E, Rugge M, Genta RM
It is primarily used to treat pyridoxine deficiency, including cases resulting from inadequate dietary intake or drug-induced deficiencies
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This orthostatic component suggests vasodilation may be significant enough in some individuals to temporarily reduce blood flow to the brain during position changes
Dietary changes often accompany the decision to supplement with B12
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