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If the appearance bothers you or if the warmth is uncomfortable, a cold compress applied for 10 to 15 minutes provides immediate relief by constricting blood vessels and reducing histamine activity at the site
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If side effects persist despite dose adjustments, physicians often recommend stopping the medication
doi: 10.1161/circgenetics.109.852814 43 WuQLiangXWangKLinJWangXWangPet al
Not tested on animals
