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The 2025 Zdrada-Nowak review in International Journal of Molecular Sciences confirmed the clinical evidence for AH-8 in wrinkle reduction, elasticity, and hydration, but flagged the specific limitation that low intrinsic skin penetration is the main efficacy ceiling for topical use [12]

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Aqueous extracts from Tenebrio molitor larval and pupal stages inhibit early hepatocarcinogenesis in vivo

Moreover, hydroquinone-loaded NLCs significantly improved skin penetration and UVA/UVB radiation protection in comparison to the hydroquinone conventional formulation (Wu et al., 2017)

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