This is often easier on the stomach than large capsules and allows for flexible dosing
[4] [6] As an antioxidant, ascorbic acid donates electrons to neutralize reactive oxygen species and free radicals, thereby protecting cellular components from oxidative damage
Enzymatic activities also play a critical role in modulating the levels of free radicals in the body [59]
Some may feel mild side effects like nausea or stomach upset
On the other hand, in cholestatic individuals in whom the NGS panels have not found pathogenic mutations, a comprehensive study like WES, performed over the full exome, can find potential gene candidates for a cholestasis association, as was the case with the most recently discovered PFIC, PFIC 13 [37, 90]
J Cell Physiol 2018;233(8):5530-5536