[9] It should be used at least 45 minutes before anticipated sexual activity
It protects somatosensory neurons in capsaicin-treated rats
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doi: 10.1093/ajcn/81.1.230S, 43
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Watch for warning signs : Contact your licensed provider if you notice persistent redness, swelling, bruising, warmth, pus or other signs of infection, as well as any unexpected side effects