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We speculate that the BPC157-FBXO22 interaction via P3 delays enzymatic degradationpeptide catabolism typically initiates with endopeptidases, followed by stepwise proteolysis into amino acids

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This proximal position of the RAMP2 ECD is conserved in AMY 2 R complexes bound to CT peptides that also have a C-terminal Pro (P32 CT ) (Fig

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