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It uniquely combines two hormone mimicsGLP-1 and GIP

risks evaluation needed

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These disorders can be associated with insulin resistance, hyperglycemia-induced damage, oxidative stress, astrocyte abnormalities, and mitochondrial dysfunction, resulting in insufficient energy supply, altered synaptic plasticity, death of neuronal cells, as well as functional and structural damage to reward networks

This is likely due to the role of vitamin B12 in energy production and metabolism