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Personalized GLP-1 Responses: Why Genetic Testing Matters The PlexusDx Precision Peptide Genetic Test analyzes GIPR (rs1800437), FTO (rs9939609), and MC4R (rs17782313) variants that relate to GLP-1 and related signaling pathways

The medications resist being degraded by DPP-4, which is the enzyme that breaks down naturally produced GLP-1 within a few minutes

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A new generation of these medications has transformed treatment possibilities for people who have type 2 diabetes (Ozempic, Mounjaro) or who have obesity or are overweight with a related health condition (Wegovy, Zepbound, Foundayo)

What youll learn: You shouldnt switch to a keto diet when first starting a GLP-1 medication

GLP-1RAs as a support for MCAS For some basics: glucagon-like peptide-1 receptor agonists (abbreviated as GLP-1 medications or as I noted above, GLP-1RAs) are a class of medications that includes semaglutide (Ozempic/Wegovy) and tirzepatide (Mounjaro/Zepbound, which also work on GIP receptors), as well as in-trials Retatrutide (a triple agonist that works on GLP-1, GIP, and Glucagon receptors)