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Description

The BMI thresholds remain identical to the injectable version

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Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K

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It activates G-protein coupled receptors FFAR2 and FFAR3 on L cells, triggering calcium influx and subsequent GLP-1 vesicle release

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Multi-systemic effects Beyond sleep, DSIP influences thermoregulation, heart rate, blood pressure, pain threshold, and immune function

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They offer convenience and needle-free dosing, but they require the same clinical attention as injectables

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Dehydration can cause headaches, fatigue, and constipation, all of which mimic or worsen GLP-1 side effects

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