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Because microdosing uses small doses, it may minimize the risk or intensity of side effects, but it still requires clinical oversight to ensure safety and effectiveness
The region is also seeing more regulatory approvals for these types of drugs, which makes them more widely available
metformin 1000 mg BID led to conflicting results on hyperandrogenism
clinical presentation is highly variable, including bland cholestasis, cholestatic hepatitis, secondary sclerosing cholangitis, and vanishing bile duct syndrome (VBDS) [64]
But theres a trade-off
Otherwise, empty stomach is best
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