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Results Molecular Dynamic simulation of the XRCC4/ Lig4 C-ter complex To get quantitative insights into the dynamics of critical residues involved in the interaction between XRCC4 and the Lig 4 C-ter domain (residues 654911), we performed a 10 ns Molecular Dynamics (MD) simulation on this complex

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While the resting -cell immunopeptidome is dominated by HLA-A-restricted peptides, IFN- largely favors HLA-B and only marginally upregulates HLA-A, translating into increased HLA-B-restricted peptide presentation and activation of HLA-B-restricted CD8 + T cells