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The oligonucleotide primers used in this study were designed and synthesized by Sangon Biotech Co., Ltd
Statements Author contributions XS: Conceptualization, Data curation, Formal analysis, Writing original draft
The 1858 C/T SNP of the PTPN22 gene is a risk factor for HT because it causes an arginine-tryptophan substitution at codon 620 (R620W), because decreased T cell signaling may results in poorer thymic elimination of autoreactive T cells, or an increased function of PTPN22 may lead to a decrease in regulatory T cells (Tregs) responsible for preventing autoimmunity
Schaefer EJ, Gregg RE, Ghiselli G, Forte TM, Ordovas JM, Zech LA, et al
This sugar-free formulation aims to help with complexion clarity and promote an even skin tone
doi: 10.1016/j.mrrev.2014.11.002 60 BirbenESahinerUMSackesenCErzurumSKalayciO
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