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However, in phase 3a trials, mean baseline Patient Health Questionnaire-9 (PHQ-9) scores for liraglutide vs placebo improved at the treatment end

Finally, although the definition of the outcome was similar across the different studies included in the quantitative analysis, it was not exactly the same

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PMID 2555512

Scientific investigations continue exploring how the body regulates: Energy utilization Nutrient processing Hormonal communication Appetite-related signaling Glucose homeostasis Physiological adaptation The growing prevalence of metabolic disorders worldwide has increased demand for research focused on understanding these systems