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Side effects are common in the first week of GLP-1 treatment as your body adjusts to the drug

GLP-1-based therapies carry an established association with increased gallbladder disease risk and rare pancreatitis (although they are extremely rate and easy to mitigate/prevent), and this observation likely extends to Retatrutide as well

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Potential penetration of liraglutide across the bloodbrain barrier was indicated by the determination of the liraglutide content in the brain via ELISA after intraperitoneal injection in mice (Hunter and Holscher 2012)

What you build inside that window determines the long-term outcome.