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Amylin and Calcitonin Receptor Pathway Satiety Enhancement Cagrilintide acts as a nonselective agonist of amylin receptors (AMY1R, AMY2R, AMY3R) and calcitonin receptor (CTR), mimicking the satiety-inducing effects of endogenous amylin[3]

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While improvements in diet and physical activity might explain some of the overall improvement, they do not account for the differences observed between the active and placebo groups

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The primary cilia of nerve cells can sense and respond to the changes of the local extracellular environment

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