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Weinrauch LA et al
Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia
Lethargy and reduced energy peak 24 hours post-dose, which is why nighttime administration is standard
In line with this, luciferase assays illustrated that exposure to U0126 or ERK1/2-specific siRNA blocked the stimulatory effect of E2 treatment via EREs in the hTERT promoter
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