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However, in this case, there are numerous obstacles to cross, mainly financial and resource barriers, intellectual properties, data access barriers, biases, and liability risks (Masuda et al., 2020)

The first approved GLP-1 analogue for clinical use was exenatide in 2005, a peptide originally isolated from Heloderma suspectum lizard venom by John Eng in 1992 [17]

doi: 10.1053/j.ackd.2014.11.004 38 MatsusakaTNiimuraFShimizuAPastanISaitoAKoboriHet al

If patients are not consuming enough calcium, vitamin D, and other bone-supporting nutrients, the risk of osteopenia or osteoporosis could increase over time

There is no separate mental-health screen, no validated PHQ-2 or PHQ-9, no follow-up, no resource referral, and no acknowledgment that the question carries different weight than the others on the same list

But like most things, too much cortisol can be a problem, and its even worse when the demand for cortisol is high over long periods of time