Tirzepatide (the active ingredient in Mounjaro/Zepbound) is a dual GLP-1 + GIP agonist, a more potent mechanism
doi: 10.1016/j.jep.2023.116305 111 ZhouCHuangJLiQZhanCXuXZhangXet al
Avram VF, Bna AM, Sima A, Aburel OM, Sturza A, Burlacu O, Timar RZ, Muntean DM, Elmr E, Creu OM (2021) Improvement of platelet respiration by cell-permeable succinate in diabetic patients treated with statins
So when we consume food, GLP-1 is released and this signals the pancreas to release insulin
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The company also states that 83% of members sustain results for one year and that members have collectively lost 1.4 million pounds