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Weight may increase slightly, partly from water retention as GLP-1 mediated effects on fluid balance normalize

Current research relies heavily on DMM or ACLT-induced murine models, which predominantly simulate post-traumatic OA

Interestingly, an altered balance of the different forms has been linked with cognitive impairment and psychiatric disorders 8,9,10

Understanding these differences helps researchers select appropriate peptides for specific experimental aims and interpret results within the context of their molecular mechanisms

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PubMed Fletcher, M.M., Halls, M.L., Christopoulos, A., Sexton, P.M., & Wootten, D