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High GPx3 expression was associated with reduced overall patient survival and increased tumor stage

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This critical balance between survival and cell death is orchestrated by the coordinated activity of the three canonical UPR branches, IRE1, PERK, and ATF6, which together determine cell fate decisions under stress

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doi: 10.1016/j.jprot.2012.12.003 27 CamejoD.Ortiz-EspnA.LzaroJ