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However, a significant challenge in evaluating kidney outcomes lies in the inconsistent definitions of renal endpoints across studies, particularly regarding the thresholds for substantial eGFR decline, which vary from 30% to 57%
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Efficacy and safety of adding the dipeptidyl peptidase-4 inhibitor alogliptin to metformin therapy in patients with type 2 diabetes inadequately controlled with metformin monotherapy: A multicentre, randomised, double-blind, placebo-controlled study
After each dose, its effects on blood sugar and appetite are strongest in the first few days and gradually weaken over the week as the medications concentration declines
Eur J Pharmacol 701: 203212
L.Ortega VillasanteC.et al
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