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Research in naturally aged mice demonstrates measurable improvements in physical performance, with treated animals showing increased running endurance and improved overall fitness metrics compared to untreated aged controls
(2016)
Washington, D.C.: National Academy Press
After the model was expanded to include GS-H 2 Q adduct formation as a function of its reduction potential, it was then combined with the Reed glutathione model 21 in order to simulate how the quinone redox-metabolism of doxorubicin influenced the glutathione metabolism
Two case reports suggest that neonates and children have a reduced propensity to toxicity following paracetamol overdose due to differences in metabolism [50, 51]
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