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It remains in Phase 3 clinical trials with approval expected in 2026-2027
It functions as a highly specific inhibitor of an enzyme called NNMT (Nicotinamide N-methyltransferase)
When B12 levels are low, it can have a direct impact on your metabolism, making it harder for your body to use or burn calories which in turn makes it harder to lose weight and keep it off
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Research shows that around 50 percent to 60 percent of ingested vitamin B12 is usually absorbed when enough intrinsic factor is present in relation to B12, but absorption decreases drastically when this ratio changes
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