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These organelles have wide range of enzymes, which significant inhibit the production of ROS
Moreover, we retrieved other relevant records 56,57,58 : two large ( N = 133,318 and N = 342,608, respectively) cohort studies in people with diabetes across 613 years noted a beneficial association between GLP-1RA prescriptions compared with non-prescription and lower diagnoses of dementia 57,58 , while a small ( N = 154 patients with T2DM) and shorter (~12 months) cross-sectional investigation of GLP-1RAs in addition to metformin, compared with metformin alone, observed better MoCA scores in the former group 56
Human insulin resistance is associated with increased plasma levels of 12-hydroxylated bile acids
Cold Spring Harb Perspect Med 1, a009316 (2011)
The ventral tegmental area The VTA is another area of interest as it is the main hub for the dopaminergic neurons of the mesolimbic dopamine system
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