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10.1136/jnnp.2005.083378 J

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Epithalon inhibits MMP-9 synthesis increased during aging of skin cells and enhances the expression of proteins Ki-67 and CD98hc that, on the other hand, need stimulation during aging

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Hence, it is well protected from UV rays, pollution, and other environmental factors that may lead to lightening of the skin

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This occurs through several potential mechanisms: IGF-1 stimulates collagen synthesis and cartilage matrix expansion Growth signalling in synovial tissue may increase fluid production Systemic effects on sodium and water handling This side effect is typically mild and reversible

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Community reports are anecdotal and do not constitute clinical evidence

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Let them warm to room temperature

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