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The patients received 1 mg, 4 mg, 8 mg, and 12 mg of retatrutide once weekly for 48 weeks compared to placebo

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The SURMOUNT-1 final results at 72 weeks showed mean weight loss of: 5 mg dose: 16.0 percent of body weight 10 mg dose: 21.4 percent of body weight 15 mg dose: 22.5 percent of body weight For context, 22.5 percent of 250 pounds is 56 pounds