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The likelihood of experiencing a deficiency in these patients was significantly increased, with a 2.45-fold risk according to a meta-analysis conducted by Niafar et al
As previously noted, NSCLC patient tumor samples showed higher expression of the different enzymes of the de novo ser/gly synthesis pathway, i.e
Some research protocols have explored doses up to 4.5 mg weekly, which showed slightly greater efficacy in the phase 2 dose-finding trial but also increased side effect burden
Lancet 395, 10331034
mild warmth or slight fatigue may occur briefly
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