5-Amino-1MQ selectively inhibits NNMT (IC50 = 1.2 M), an enzyme that consumes nicotinamide by methylating it
Low levels of B12 can also be associated with those who have anemia or certain autoimmune disorders, and some prescription medications can also interfere with vitamin absorption
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By blocking NNMT, 5-Amino-1MQ increases NAD+ levels and activates SIRT1, the longevity gene, promoting fat loss, energy production, and metabolic rejuvenation