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Launched by Novo Nordisk in 2026, semaglutide in its oral form became the first GLP-1 drug intended specifically for weight loss, contrasting with Rybelsus, which is used primarily for type 2 diabetes

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In one experiment, obese Zucker rats lost around 50% of their weight in 19 days, with the researchers noting 23% increased lipolytic activity, measured as glycerol release from the fatty tissue of the treated animals [20]

You are also more likely to develop depression and obesity

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Expiration dates are an important indicator of how long a vial of semaglutide lasts