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There are three different UPR signaling pathways in ERS response that are mediated by (1) RNA-dependent protein kinase-like ER kinase (PERK), (2) activated transcription factor 6 (ATF6), and (3) inositol-required enzyme 1 (IRE1) (69)

10.1007/s13105-016-0492-6 J

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Insulin resistance the hinge between hypertension and type 2 diabetes

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Figure 6 Mitochondrial Functional Markers There was no significant difference in MnSOD, Tom-20 and OXPHOS complexes among the three groups at P1 (Figures 7A,D,G)