Glucagon-like peptide-1 (GLP-1) is an incretin hormone produced primarily by intestinal L-cells in response to food intake
They also disclose the various potential routes of administration for using semaglutide in a product, including lingual, sublingual, oral and parenteral
Jamalpoor A, van Gelder CA, Yousef Yengej FA, Zaal EA, Berlingerio SP, Veys KR, Pou Casellas C, Voskuil K, Essa K, Ammerlaan CM, Rega LR, van der Welle RE, Lilien MR, Rookmaaker MB, Clevers H, Klumperman J, Levtchenko E, Berkers CR, Verhaar MC, Altelaar M, Masereeuw R, Janssen MJ (2021) Cysteamine-bicalutamide combination therapy corrects proximal tubule phenotype in cystinosis
For instance, an overweight individual may find that 1.21.5 g/kg (using actual body weight) is sufficient for muscle maintenance
doi: 10.1038/s41598-020-69606-7 67 GirmaA
Nat Aging 5 , 960961 (2025)