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At the genomic level, Epitalon modulated the expression of key circadian rhythm genes: Clock expression in leukocytes decreased 1.8-fold, Cry2 expression doubled, and Csnk1e expression in lymphocytes decreased by 2.1-fold, all with statistical significance
Health Canada has not evaluated these compounds for safety or efficacy in treating any medical condition
Sleep problems Higher doses can increase the risk of sleep disturbances (Strawn et al., 2018)
A historical review of brain drug delivery
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