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No FDA approval: IGF-1 LR3 has never received regulatory approval for human therapeutic use and is restricted to research applications [12]
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Approximately half of the psammomatous cases are associated with CC, an autosomal dominant genetic disease harboring a chromosome 17 mutation that affects the cAMP-dependent protein kinase type I regulatory subunit alpha ( PRKAR1A ) gene ( PRKAR1A gene mutation (55)
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