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If symptoms suggest a new endocrine problem, baseline testing is reasonable before starting therapy, with a follow-up check at three months for the standard panels: HbA1c, fasting glucose, TSH, and free T4 if on thyroid therapy, morning cortisol only when clinically indicated, and sex hormones if symptoms arise

Ten to twelve years is a relatively short period of time to study the long-term effects of a new class of drugs

The protein concentration of the samples was measured by BCA protein assay

Access and affordability: The high cost of GLP-1 drugs remains a significant hurdle for patients and payers

GLP-1 injections can have a similar impact for people who historically struggle to maintain a healthy relationship with food

This allows assessment of how much improvement persists after the peptide clears the system