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The STEP trial extensions tracked semaglutide use for three years with consistent safety profiles

Kim, PhD

Progress Timeline: Ideal Candidates: Individuals with dull or sun-damaged skin

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Pathogenesis An increased number of melanocytes within the basal layer of the epidermis leads to an increased production of melanin, resulting in hyperpigmented macules

Most healthcare providers recommend restarting at 2.5 mg weekly or one step below your previous maintenance dose, then gradually increasing every 4 weeks to minimize gastrointestinal side effects while restoring therapeutic benefits