Consider the enhanced potency of IGF-1 LR3 compared to native IGF-1 when designing experimental protocols
Alanine and pyroglutamic acid were significantly associated with an alteration of glutathione metabolism
Dean OM, van den Buuse M, Bush AI, Copolov DL, Ng F, Dodd S, Berk M
Results reported were the usual, weight loss, cardiometabolic markers and vitals
Clinical trials have demonstrated efficacy across diverse body mass index (BMI) ranges
Based on reading some of the websites it seems that their hypothesis is that because ALC is involved in the Krebs cycle in the mitochondria, which gets energy from fatty acids, that means ALC helps burn fat. There is not much in the scientific literature on this topic, but I did come across an article that found no difference in metabolic parameters in study participants taking L-carnitine versus controls (not exactly the same things as acetyl-L-carnitine, but they are used somewhat similarly in the body, there just isnt the extra acetyl group in the L-carnitine)