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The median follow-up duration was 1 year (IQR: 0.52 years), with key findings including a median weight loss of 11.7 kg and a median BMI at the most recent follow-up of 31.2 kg/m 2 , reflecting a median reduction of 3.7 kg/m 2

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GLP-1R action on brown adipose tissue (BAT) thermogenesis In addition to causing changes in feeding, central GLP-1R activation may regulate body weight by increasing brown adipose tissue (BAT) thermogenesis (reviewed in Lockie et al., 2013)

However, they also dont last as long, so the medication must be taken daily instead of weekly to maintain the drugs effects

In another study performed to examine the potential cardioprotective effects in elderly hearts, a model of aging rats was used in which the effects were tested in aged rats

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