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Thus, it is recommended to investigate for this AE in SGLT2i-treated patients with symptoms of ketoacidosis, such as nausea, vomiting, abdominal pain, ketonuria, and/or ketonemia, regardless of the current glucose status [74]
Adverse events followed the same gastrointestinal pattern: diarrhea (30.1% / 24.4% at 9 / 12 mg vs 8.7% on placebo), nausea (21.7% / 22.4% vs 5.8%) and dysesthesia (6.4% / 6.4% vs 1.3%)
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