doi: 10.1097/MD.0000000000021464 78
Injecting into fat instead of muscle reduces absorption, so the dose may not work as intended
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tremor, tachycardia) Asthma/COPD: 2 blockade may precipitate bronchospasm , especially with non-selective agents Peripheral arterial disease: Reduced 2-mediated vasodilation may worsen claudication Psoriasis: beta blockers can exacerbate pre-existing psoriasis Adverse Effects Adverse effects reflect blockade of receptors in non-cardiac tissues and include the following: Bronchospasm (2 blockade) Bradycardia Cold extremities and Raynauds phenomenon Hypotension Fatigue and dizziness Sleep disturbance (lipophilic drugs) including nightmares Erectile dysfunction Interactions Beta-blockers have several important drug interactions that may affect respiratory and cardiovascular function